Synthesis and Characterization of Some Pyrimidine Derivatives from Dimethyl Malonate and Evaluation their Biological Activity

Sajed Khalil Mahmood , Malath Khalaf Rasheed

Please use this identifier to cite or link to this item: http://148.72.244.84:8080/xmlui/handle/xmlui/3679

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DC Field	Value	Language
dc.contributor.author	Sajed Khalil Mahmood , Malath Khalaf Rasheed	-
dc.date.accessioned	2023-10-16T10:20:37Z	-
dc.date.available	2023-10-16T10:20:37Z	-
dc.date.issued	2019	-
dc.identifier.citation	http://dx.doi.org/10.24237/djps.15.02.494B	en_US
dc.identifier.issn	2222-8373	-
dc.identifier.uri	http://148.72.244.84:8080/xmlui/handle/xmlui/3679	-
dc.description.abstract	In this research of some new pyrimidine derivatives were synthesized by reaction of dimethyl malonate with different aldehydes (Cinnamaldehyde, Vanilline, Naphthaldehyde or Furfural) and urea, Thiourea or Thiosemicarbazide in three-component Biginelli reaction with good yield and signed as (A1-A10). These compounds were synthesized via microwave irradiation by using modified domestic microwave oven. Some of the newly synthesized compounds exhibited antibacterial and antifungal activity. The structure of the synthesized compounds were confirmed by physical and spectra 13C/1H-NMR and FTIR.	en_US
dc.description.sponsorship	https://djps.uodiyala.edu.iq/	en_US
dc.language.iso	en	en_US
dc.publisher	University of Diyala	en_US
dc.subject	Keywords: Pyrimidine, Diethyl malonate, Biginelli reactions, modified domestic microwave oven.	en_US
dc.title	Synthesis and Characterization of Some Pyrimidine Derivatives from Dimethyl Malonate and Evaluation their Biological Activity	en_US
dc.title.alternative	تحضير وتشخيص بعض مشتقات البيرميدين المشتقة من ثنائي مثيل مالونيت وتقييم فعاليتها الحيوية	en_US
dc.type	Article	en_US
Appears in Collections:	مجلة ديالى للعلوم الاكاديمية / Academic Science Journal (Acad. Sci. J.)

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