Antimicrobial activity of Borago officinalis leaves extract against Staphylococcus Spp. and Streptococcus pyogenes

Abstract

The current study was conducted to evaluate the antimicrobial activity of Aqueous and alcoholic extracts (hot) of Borago officinallis leaves against types of bacteria that include Staphylococcus aureus, Staphylococcus epidermides and Streptococcus payogene, the results showed inhibitory effect of both extracts against bacteria. A photochemical screening of both extracts was revealed the presence of (Tannins, Alkaloids, Risine , Saponin , Phenols , Flavonoides and Glycosides). Sensitivity test of isolates to antibiotics was studied and most of them were resistance to Ceftazidim, Chloramphinicol, Cefotaxime, Amoxicillin and Ampicillin. Most of isolates were sensitive to Amoxicillin /Clavulanic acid and Penicillin (G). All the isolates showed high sensitivity to Norfloxacin and Gentamicine 100%. The results show Synergism effect when Combination of Ceftazidime and Amoxicillin with hot (aqueous and alcoholic) extracts of Borago officinalis on the different type of bacteria.