Agaricus bisporous effect on Sugar, Cholesterol and the Bactericidal power of human serum

Abstract

This research was carried out to study the effect of Agaricus bisporous mushroom on reducing the sugar and cholesterol in blood and determine its activity on improving the bactericidal power of serum collected from a group of healthy volunteers. So, about fifty healthy volunteers from both sexes ranging in age from (20-30 years) and of a weight between (65-100 kg) were included in this study. Results of nourishing (150g) of Agaricus bisporus mushroom as a diet to about (40) healthy volunteers from both sexes twice a week for two months did not show any change in body weight mass (BW) compared with the controls after two months of mushroom administration. However, a significant difference (P <0.05) in serum glucose and cholesterol concentrations in both (male and female volunteers of the study) was detected. In addition, the effect of Agaricus bisporus mushroom administration on the bactericidal activity of normal serum was also studied and a significant difference (P <0.05) in the bacterial colony counts especially in the colony counts of the bacterium Staphylococcus aureus was recorded. Moreover, the ethanolic extract of the Agaricus bisporous mushroom showed a significant (P <0.05) antibacterial activity against Staphylococcus aureus strains only