EVALUATION OF SEROPREVALENCE OF HERPES SIMPLEX VIRUS IgG ANTIBODY IN BAQUBA CITY BY USING ELISA TECHNIQUE

Abstract

Herpes simplex virus infection is a viral infection caused by herpes simplex virus , which infect the skin and mucous membrane , which is of two types (HSV-1 & HSV-2) , type one is the common infection , both sex are affected , type-1(labial) most commonly seen in childhood and type-2 (genital) in adulthood which is sexually transmitted. The aim of the present study was to evaluate the seroprevalance of herpes simplex virus infection among Iraqi population. A cross sectional study , in which (398) persons (200) healthy volunteers and (198) with different skin disease (except HSV infections) were included , during the period from the first of January to the first of Jullay 2013 in Baquba city and outpatient clinic of Baquba Teaching Hospital , their ages ranged from (1-60) years , they were (187) males and (154) females . Blood samples were taken from all persons , to identify the IgG antibody for the herpes simplex virus type 1 and 2 ,by using ELISA technique in Baquba city . Certain data regarding sex , address, education and occupation were recorded .The study showed that (315) (79.09%) of evaluated persons were positive for anti-herpes simplex virus IgG antibody with (P<0.001) and more prevalent in females (40.4%) than males (38.69%) , predominantly in age group (21-40 years )(39.6%) , with a significant differences (P<0.001) and more prevalent in civilized and those of low education levels (P<0.001) . Also the HSV-1 antibody was more prevalent (56.51%) than HSV-2 (43.45%) , without significant value .