Exploiting of Cordia dichotoma Aqueous-Methanol Extract to Reduce Effect of Aspirin Against Gastric Mucosa of Rabbit, Oryctolagus cuniculus

Abstract

Ulcer is an inflammatory break reaction in the mucous membrane of stomach. The results showed non- significant changes in most clinical, hematological parameters depended in the experiment. While the biochemical; parameters exhibited a significant change. Prevent index was (27.08%). The level of pH of stomach, volume of gastric fluid, free acidity and total acidity levels, showed a significant change. Gastric mucosa was more severely affected and showed more severe and numbers of lesion in those exposed to aspirin alone, then in aspirin and plant extract. Aqueous – methanol extract of Cordia dichotoma fruit showed mild gastric protection against aspirin induced ulcer.