The Role of Plasma Homocysteine Level in Leukemia Disease and its Relationship with the Blood Component The White Blood Cell and Hemoglobin in Patients Tikrit-Iraq.

Abstract

verall this paper to investigate the relation Homocysteine (Hcy), WBC, and Hemoglobin with Leukemia (Blood cancer) disease.Studies of Iraqi men in Tikrit Hospital. Leukemia and is characterized by an abnormal proliferation of blood cells, white blood cells (leukocytes). Objectives: To investigate homocysteine levels in Leukemia disease and its relationship with White blood cells(WBC) and Hemoglobin (Hb)( repeated).Methods: This investigation performed as a case control study for two groups as 40 Leukemia patients and 25 as a control. Patients for two group in Tikrit-Iraq. Leukemia patients were selected based on the criteria of the American Psychological Association. plasma homocysteine level were measured by HPLC method at UV detector 338nm WBC and Hb were measured by method Manual blood count Hemacytometer is a counting chamber according to WHO. Results: 40 Patients in group1 plasma Homocysteine was 21.15±8.9 μmol/L, but in control group plasma Homocysteine was 12.00±4.33 (p=0.83). The average plasma homocysteine level in the group 2 of patients was 10.56±3.99μmol/L, Homocysteine in the control group 2 was 28.11±9.75μmol/l, (p=0.78). Conclusion: The average plasma homocysteine level in Leukemia patients was higher than in the control group; however, it shows a significant relationship with the WBC and H